ChromosOmics - Database
tl_files/tiny_templates/Bilder
                          TL/sSMC-book.jpg tl_files/tiny_templates/Bilder
                          TL/hetmorh-book.jpg

                                                  X-CHROMOSOME  -                                                 
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In general 70% of sSMC carriers are clinically normal. The figures listed above
are based on the bias, that mainly clinically aberrant cases are studied and reported in literature!


UPD (uniparental disomy) cases: UPD(X)mat UPD(X)pat UPD(X)mat or pat

the probably non-dosage sensitive pericentric region of X-chromosome

schematic

cytogenetic

depiction


short (= p-) arm het long (= q-) arm

























































p11.4
p11.2 cen

q13 q21








































































































































































































































no clinical
signs


























































































clinical
signs





















































schematic

molecular-

cytogenetic

depiction




critical
region
p-arm
uncritical
region
p-arm
centromere uncritical
region
q-arm
critical
region
q-arm
NCBI 36/ hg18 50.90 56.60 56.60 - 65.10 65.10 unknown
GRCh 37/ hg19 50.91 58.10 58.10 - 64.60 64.60 unknown
  Positions given in megabasepair (Mbp)
acc. to cases marked as ***